Dr. Chang is a world authority in the use of advanced radiation therapy techniques in the treatment of a variety of benign conditions and malignant tumors of the central nervous system. He is highly experienced in handling both routine cases, and the most complex cases requiring radiotherapeutic evaluation in a multi-disciplinary setting of experts comprising neuro-radiation oncologists, neurosurgeons and neuro-oncologists, and neuro-radiologists.

Dr. Chang received his undergraduate degree in Biology from the Massachusetts Institute of Technology and medical doctorate degree from Harvard Medical School. His internship in medicine at the California Pacific Medical Center at UC San Francisco and residency training was performed at the Harvard Joint Center for Radiation Therapy, in Boston, Massachusetts. He served on the faculty at MD Anderson Cancer Center for over 12 years and held the academic rank of Professor and Director of the CNS Stereotactic Radiation Program. He has held national leadership roles including having served as member and Chair of the M. D. Anderson Cancer Center Clinical Research Committee (CRC). He served as CNS track leader for the American Society for Clinical Oncology (ASCO) Scientific Program Committee, and member of the ASCO Cancer Education Committee. Dr. Chang has served as the co-leader for the American Society of Radiation Oncology (ASTRO) brain metastasis guidelines development task force and as a member of the Annual Program Committee of the Educational Council of ASTRO. He is past Chair of the American Radium Society Appropriate Use Committee (AUC) for Brain and has been designated as a Fellow of the American Radium Society in 2022. He has been listed in the Best Doctors Directory and America’s Top Doctors for Cancer in Castle Connolly Medical Ltd. He has been named Fellow of the American Society of Radiation Oncology. Dr. Chang led a phase III randomized controlled trial on brain metastasis published in the Lancet Oncology which has helped to change the practice patterns for metastatic brain disease. Dr. Chang has been selected as a plenary speaker for past meetings of ASTRO and the American Association for Neurological Surgeons (AANS). He has authored or co-authored over 200 peer-reviewed published medical journal papers. Dr. Chang currently serves as chairman and Professor of the Department of Radiation Oncology and Medical Director for the Radiation Oncology Clinics at Keck Medicine, and at Children's Hospital Los Angeles, and co-director of the Keck Medicine gamma knife radiosurgery program.